Tiotropium has been shown to improve lung function, quality of life, and exacerbations and reduce mortality when compared with placebo in COPD. It remains unclear whether benefits are seen when tiotropium is used in conjunction with inhaled corticosteroids (ICSs) plus long-acting ß-agonists (LABAs).
- Obstructive pulmonary disease
Short, P. M., Williamson, P. A., Elder, D. H. J., Lipworth, S. I. W., Schembri, S., & Lipworth, B. J. (2012). The impact of tiotropium on mortality and exacerbations when added to inhaled corticosteroids and long-acting β-agonist therapy in COPD. Chest, 141(1), 81-86. https://doi.org/10.1378/chest.11-0038