TY - JOUR
T1 - The Incidence and Risk of Biochemical Recurrence Following Radical Radiotherapy for Prostate Cancer in Men on Angiotensin-Converting Enzyme Inhibitors (ACEIs) or Angiotensin Receptor Blockers (ARBs)
AU - Alashkham, Abduelmenem
AU - Paterson, Catherine
AU - Windsor, Phyllis
AU - Struthers, Allan
AU - Rauchhaus, Petra
AU - Nabi, Ghulam
N1 - Funding: Prostate Cancer, UK grant number PG12-39.
PY - 2016/10
Y1 - 2016/10
N2 - Micro-Abstract Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are anti-hypertensive medication and have been linked to prostate cancer, but their effect on biochemical recurrence (BR) remains unexplored. The aims of the study were to evaluate the incidence and risk of BR in men receiving ACEIs/ARBs after radical radiotherapy with adjuvant∖neoadjuvant hormone treatment. The administration of ACEIs/ARBs were associated with a reduced risk of BR.
AB - Micro-Abstract Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are anti-hypertensive medication and have been linked to prostate cancer, but their effect on biochemical recurrence (BR) remains unexplored. The aims of the study were to evaluate the incidence and risk of BR in men receiving ACEIs/ARBs after radical radiotherapy with adjuvant∖neoadjuvant hormone treatment. The administration of ACEIs/ARBs were associated with a reduced risk of BR.
KW - Biochemical recurrence
KW - Hormonal therapy
KW - Prostate cancer
KW - Radiotherapy
KW - Renin angiotensin system
UR - http://www.scopus.com/inward/record.url?scp=84961879934&partnerID=8YFLogxK
U2 - 10.1016/j.clgc.2016.03.009
DO - 10.1016/j.clgc.2016.03.009
M3 - Article
C2 - 27053500
AN - SCOPUS:84961879934
SN - 1558-7673
VL - 14
SP - 398
EP - 405
JO - Clinical Genitourinary Cancer
JF - Clinical Genitourinary Cancer
IS - 5
ER -