The incidence of motor nueron disease in Scotland

TY - JOUR

T1 - The incidence of motor nueron disease in Scotland

AU - Forbes, Raeburn B.

AU - Colville, Shuna

AU - Parratt, John

AU - Swingler, Robert J.

PY - 2007

Y1 - 2007

N2 - Between 1989 and 1998, 1226 cases of ALS/MND were identified in Scotland, with mean age of onset 65.2 (SD 11.9) years for men and 67.2 (SD 11.0) for women. Annual standardized incidence was 2.40 per 100,000 (95% CI 2.22-2.58). Using capture recapture methods we confirm a high level of case ascertainment for each year of study. Incidence and ascertainment of ALS has remained stable in a large population over a prolonged period of time. Large population-based databases can be used to test aetiological hypotheses.

AB - Between 1989 and 1998, 1226 cases of ALS/MND were identified in Scotland, with mean age of onset 65.2 (SD 11.9) years for men and 67.2 (SD 11.0) for women. Annual standardized incidence was 2.40 per 100,000 (95% CI 2.22-2.58). Using capture recapture methods we confirm a high level of case ascertainment for each year of study. Incidence and ascertainment of ALS has remained stable in a large population over a prolonged period of time. Large population-based databases can be used to test aetiological hypotheses.

KW - Adolescent

KW - Adult

KW - Age Factors

KW - Aged

KW - Aged, 80 and over

KW - Amyotrophic Lateral Sclerosis

KW - Child

KW - Female

KW - Humans

KW - Incidence

KW - Male

KW - Middle Aged

KW - Motor Neuron Disease

KW - Reference Values

KW - Scotland

U2 - 10.1007/s00415-006-0454-y

DO - 10.1007/s00415-006-0454-y

M3 - Article

C2 - 17420925

SN - 0340-5354

VL - 254

SP - 866

EP - 869

JO - Journal of Neurology

JF - Journal of Neurology

IS - 7

ER -