The intertwined roles of specialized metabolites within the Bacillus subtilis biofilm

Margarita Kalamara, Nicola R. Stanley-Wall (Lead / Corresponding author)

Research output: Contribution to journalComment/debatepeer-review

5 Citations (Scopus)
87 Downloads (Pure)


Bacteria produce specialized metabolites with a range of functions. In this issue of the Journal of Bacteriology, Schoenborn et al. study the production and role of secondary metabolites during biofilm development and sporulation in Bacillus subtilis (A. A. Schoenborn, S. M. Yannarell, E. D. Wallace, H. Clapper, et al., J Bacteriol 203:e00337-21, 2021, -21). Most metabolites studied are produced during differentiation, and six are required for the development of biofilms and/or spores. The authors propose a model for the timing of production and role in differentiation exerted by each secondary metabolite.

Original languageEnglish
Article numbere00431-21
Number of pages12
JournalJournal of Bacteriology
Issue number22
Early online date30 Aug 2021
Publication statusPublished - 25 Oct 2021


  • Bacillus subtilis
  • Biofilm
  • Differentiation
  • Specialized metabolites
  • Spore

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology


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