The Micro-Elimination Approach to Eliminating Hepatitis C: Strategic and Operational Considerations

TY - JOUR

T1 - The Micro-Elimination Approach to Eliminating Hepatitis C

T2 - Strategic and Operational Considerations

AU - Lazarus, Jeffrey V.

AU - Safreed-Harmon, Kelly

AU - Thursz, Mark R.

AU - Dillon, John F.

AU - El-Sayed, Manal H.

AU - Elsharkawy, Ahmed M.

AU - Hatzakis, Angelos

AU - Jadoul, Michel

AU - Prestileo, Tullio

AU - Razavi, Homie

AU - Rockstroh, Jürgen K.

AU - Wiktor, Stefan Z.

AU - Colombo, Massimo

N1 - Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

PY - 2018/8/1

Y1 - 2018/8/1

N2 - The introduction of efficacious new hepatitis C virus (HCV) treatments galvanized the World Health Organization to define ambitious targets for eliminating HCV as a public health threat by 2030. Formidable obstacles to reaching this goal can best be overcome through a micro-elimination approach, which entails pursuing elimination goals in discrete populations through multi-stakeholder initiatives that tailor interventions to the needs of these populations. Micro-elimination is less daunting, less complex, and less costly than full-scale, country-level initiatives to eliminate HCV, and it can build momentum by producing small victories that inspire more ambitious efforts. The micro-elimination approach encourages stakeholders who are most knowledgeable about specific populations to engage with each other and also promotes the uptake of new models of care. Examples of micro-elimination target populations include medical patients, people who inject drugs, migrants, and prisoners, although candidate populations can be expected to vary greatly in different countries and subnational areas.

AB - The introduction of efficacious new hepatitis C virus (HCV) treatments galvanized the World Health Organization to define ambitious targets for eliminating HCV as a public health threat by 2030. Formidable obstacles to reaching this goal can best be overcome through a micro-elimination approach, which entails pursuing elimination goals in discrete populations through multi-stakeholder initiatives that tailor interventions to the needs of these populations. Micro-elimination is less daunting, less complex, and less costly than full-scale, country-level initiatives to eliminate HCV, and it can build momentum by producing small victories that inspire more ambitious efforts. The micro-elimination approach encourages stakeholders who are most knowledgeable about specific populations to engage with each other and also promotes the uptake of new models of care. Examples of micro-elimination target populations include medical patients, people who inject drugs, migrants, and prisoners, although candidate populations can be expected to vary greatly in different countries and subnational areas.

KW - health policy

KW - health systems

KW - hepatitis C

KW - micro-elimination

KW - models of care

KW - Delivery of Health Care, Integrated/legislation & jurisprudence

KW - Global Health/legislation & jurisprudence

KW - Prevalence

KW - Hepatitis C/ethnology

KW - Humans

KW - Models, Organizational

KW - Risk Factors

KW - Cooperative Behavior

KW - Disease Eradication/legislation & jurisprudence

KW - International Cooperation

KW - Vulnerable Populations

KW - Stakeholder Participation

KW - Interdisciplinary Communication

KW - Antiviral Agents/therapeutic use

KW - Health Policy/legislation & jurisprudence

KW - Policy Making

U2 - 10.1055/s-0038-1666841

DO - 10.1055/s-0038-1666841

M3 - Article

C2 - 29986353

SN - 0272-8087

VL - 38

SP - 181

EP - 192

JO - Seminars in Liver Disease

JF - Seminars in Liver Disease

IS - 3

ER -