The permeability of artificial dentine carious lesions

T. O. Elgalaid, S. L. Creanor, S. Creanor, A.F. Hall

    Research output: Contribution to journalArticlepeer-review

    2 Citations (Scopus)


    Objective: This study aimed to verify whether two demineralisation solutions, with different fluoride concentrations, would produce subsurface lesions in dentine, as assessed by microradiography, with different mineral loss profiles and, subsequently, to determine the dentine permeability of the two altered tissues.

    Methods: Forty-five human coronal portions were prepared and randomly divided into two test groups (20 specimens each) with the remaining five as a control group. Each test group was exposed to a demineralisation solution containing either 1 or 5 ppm fluoride for five days.

    Results: There were highly significant differences between the two test groups for all microradiographic parameters, except for lesion depth. The increase in dentine penneability from baseline to day 5 was statistically significant within each of the two test groups, but not for the control group.

    Conclusion: The differences in the mineral content profile of the two lesions did not influence the magnitude of change in their permeability. (C) 2008 Elsevier Ltd. All rights reserved.

    Original languageEnglish
    Pages (from-to)744-750
    Number of pages7
    JournalArchives of Oral Biology
    Issue number8
    Publication statusPublished - Aug 2008


    • dentinal tubules
    • dentine permeability
    • artificial dentine caries
    • transverse microradiography
    • IN-VITRO
    • ENAMEL


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