The pharmacological treatment of acquired nystagmus

Arpan R Mehta, Christopher Kennard (Lead / Corresponding author)

Research output: Contribution to journalReview articlepeer-review

19 Citations (Scopus)

Abstract

We review the latest literature on the neuropharmacological treatments for acquired nystagmus.Nystagmus may have a significant [corrected] impact on health, yet there is little scientific evidence on which to make firm recommendations for treatment. Acquired pendular nystagmus may respond to gabapentin or memantine; downbeat and upbeat nystagmus to aminopyridines; and periodic alternating nystagmus to baclofen. To improve treatment we need multi-centre, randomised controlled trials using standardised techniques in reporting objective outcomes, with good follow-up duration and careful reporting of side effects.

Original languageEnglish
Pages (from-to)147-153
Number of pages8
JournalPractical Neurology
Volume12
Issue number3
DOIs
Publication statusPublished - Jun 2012

Keywords

  • Amines/therapeutic use
  • Aminopyridines/therapeutic use
  • Baclofen/therapeutic use
  • Cyclohexanecarboxylic Acids/therapeutic use
  • Gabapentin
  • Humans
  • Memantine/therapeutic use
  • Nystagmus, Congenital/diagnosis
  • Nystagmus, Pathologic/diagnosis
  • Randomized Controlled Trials as Topic/methods
  • Treatment Outcome
  • gamma-Aminobutyric Acid/therapeutic use

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