The renaissance of GSK3

Philip Cohen, Sheelagh Frame

    Research output: Contribution to journalReview article

    1175 Citations (Scopus)

    Abstract

    Glycogen synthase kinase 3 (GSK3) was initially described as a key enzyme involved in glycogen metabolism, but is now known to regulate a diverse array of cell functions. The study of the substrate specificity and regulation of GSK3 activity has been important in the quest for therapeutic intervention.

    Original languageEnglish
    Pages (from-to)769-776
    Number of pages8
    JournalNature Reviews Molecular Cell Biology
    Volume2
    Issue number10
    DOIs
    Publication statusPublished - 1 Oct 2001

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