The role of aldosterone in heart failure and the clinical benefits of aldosterone blockade

Adelle Dawson, Justine I Davies, Allan D Struthers

    Research output: Contribution to journalArticle

    5 Citations (Scopus)

    Abstract

    Aldosterone has a variety of detrimental effects on the heart and vasculature and is increasingly recognized as an important target in chronic heart failure, as illustrated by the Randomized Aldactone Evaluation Study. In this article, the evidence supporting the cardiovascular effects of aldosterone in humans and the proven benefits of aldosterone-receptor antagonists in heart failure shall be discussed.
    Original languageEnglish
    Pages (from-to)29-36
    Number of pages8
    JournalExpert Review of Cardiovascular Therapy
    Volume2
    Issue number1
    DOIs
    Publication statusPublished - 2004

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