The role of aldosterone in heart failure and the clinical benefits of aldosterone blockade

Adelle Dawson; Justine I Davies; Allan D Struthers

doi:10.1586/14779072.2.1.29

The role of aldosterone in heart failure and the clinical benefits of aldosterone blockade

Adelle Dawson, Justine I Davies, Allan D Struthers

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Aldosterone has a variety of detrimental effects on the heart and vasculature and is increasingly recognized as an important target in chronic heart failure, as illustrated by the Randomized Aldactone Evaluation Study. In this article, the evidence supporting the cardiovascular effects of aldosterone in humans and the proven benefits of aldosterone-receptor antagonists in heart failure shall be discussed.

Original language	English
Pages (from-to)	29-36
Number of pages	8
Journal	Expert Review of Cardiovascular Therapy
Volume	2
Issue number	1
DOIs	https://doi.org/10.1586/14779072.2.1.29
Publication status	Published - 2004

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10.1586/14779072.2.1.29

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title = "The role of aldosterone in heart failure and the clinical benefits of aldosterone blockade",

abstract = "Aldosterone has a variety of detrimental effects on the heart and vasculature and is increasingly recognized as an important target in chronic heart failure, as illustrated by the Randomized Aldactone Evaluation Study. In this article, the evidence supporting the cardiovascular effects of aldosterone in humans and the proven benefits of aldosterone-receptor antagonists in heart failure shall be discussed.",

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AB - Aldosterone has a variety of detrimental effects on the heart and vasculature and is increasingly recognized as an important target in chronic heart failure, as illustrated by the Randomized Aldactone Evaluation Study. In this article, the evidence supporting the cardiovascular effects of aldosterone in humans and the proven benefits of aldosterone-receptor antagonists in heart failure shall be discussed.

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JO - Expert Review of Cardiovascular Therapy

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The role of aldosterone in heart failure and the clinical benefits of aldosterone blockade

Abstract

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