TY - JOUR
T1 - The role of MCM/P1 proteins in the licensing of DNA replication
AU - Chong, James P. J.
AU - Thömmes, Pia
AU - Blow, J. Julian
PY - 1996/3
Y1 - 1996/3
N2 - The DNA replication licensing system ensures that eukaryotic chromosomes replicate precisely once per cell cycle. A central component of the licensing system, RLF-M, has recently been shown to consist of a complex of Mcm/P1 proteins. This result allows us to integrate data about the MCM/P1 family obtained in different eukaryotes, ranging from yeast to man, into a general picture of the way that chromosome replication is controlled.
AB - The DNA replication licensing system ensures that eukaryotic chromosomes replicate precisely once per cell cycle. A central component of the licensing system, RLF-M, has recently been shown to consist of a complex of Mcm/P1 proteins. This result allows us to integrate data about the MCM/P1 family obtained in different eukaryotes, ranging from yeast to man, into a general picture of the way that chromosome replication is controlled.
U2 - 10.1016/S0968-0004(96)10013-X
DO - 10.1016/S0968-0004(96)10013-X
M3 - Article
C2 - 8882583
SN - 0968-0004
VL - 21
SP - 102
EP - 106
JO - Trends in Biochemical Sciences
JF - Trends in Biochemical Sciences
IS - 3
ER -