The role of neutrophils in cystic fibrosis

Alison M Gifford, James D. Chalmers (Lead / Corresponding author)

    Research output: Contribution to journalArticlepeer-review

    61 Citations (Scopus)

    Abstract

    Neutrophils are known to dominate the pulmonary inflammatory process observed in cystic fibrosis (CF). An enduring paradox is how these large numbers of neutrophils fail to eradicate colonizing bacteria. Major advances in our understanding of neutrophil dysfunction in CF and its effect on the innate immune system are leading to advances in our understanding of the pathophysiology and leading directly to new therapies.
    Original languageEnglish
    Pages (from-to)16-22
    Number of pages7
    JournalCurrent Opinion in Hematology
    Volume21
    Issue number1
    DOIs
    Publication statusPublished - Jan 2014

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