The role of serine/threonine kinases in T-cell activation

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    17 Citations (Scopus)

    Abstract

    Signalling through serine/threonine kinases is a key mechanism that regulates immune cell development, activation and effector functions. An emerging theme is that serine kinases do not act in isolation, but function in a complex overlapping network. Understanding the molecular targets of serine kinases as well as their links to other serine kinases is key to advancing our understanding of the intracellular signalling pathways that link immune receptors with the gene transcriptional programs that control the immune system in vivo.
    Original languageEnglish
    Pages (from-to)314-320
    Number of pages7
    JournalCurrent Opinion in Immunology
    Volume18
    Issue number3
    DOIs
    Publication statusPublished - Jun 2006

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