The role of serine/threonine kinases in T-cell activation

Sharon A. Matthews; Doreen A. Cantrell

doi:10.1016/j.coi.2006.03.006

The role of serine/threonine kinases in T-cell activation

Sharon A. Matthews, Doreen A. Cantrell

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Signalling through serine/threonine kinases is a key mechanism that regulates immune cell development, activation and effector functions. An emerging theme is that serine kinases do not act in isolation, but function in a complex overlapping network. Understanding the molecular targets of serine kinases as well as their links to other serine kinases is key to advancing our understanding of the intracellular signalling pathways that link immune receptors with the gene transcriptional programs that control the immune system in vivo.

Original language	English
Pages (from-to)	314-320
Number of pages	7
Journal	Current Opinion in Immunology
Volume	18
Issue number	3
DOIs	https://doi.org/10.1016/j.coi.2006.03.006
Publication status	Published - Jun 2006

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10.1016/j.coi.2006.03.006

Royal Society Dorothy Hodgkin Research Fellowship (2003-2007)
Matthews, S. (Recipient), 2003
Prize: Fellowship awarded competitively

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title = "The role of serine/threonine kinases in T-cell activation",

abstract = "Signalling through serine/threonine kinases is a key mechanism that regulates immune cell development, activation and effector functions. An emerging theme is that serine kinases do not act in isolation, but function in a complex overlapping network. Understanding the molecular targets of serine kinases as well as their links to other serine kinases is key to advancing our understanding of the intracellular signalling pathways that link immune receptors with the gene transcriptional programs that control the immune system in vivo.",

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AU - Cantrell, Doreen A.

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AB - Signalling through serine/threonine kinases is a key mechanism that regulates immune cell development, activation and effector functions. An emerging theme is that serine kinases do not act in isolation, but function in a complex overlapping network. Understanding the molecular targets of serine kinases as well as their links to other serine kinases is key to advancing our understanding of the intracellular signalling pathways that link immune receptors with the gene transcriptional programs that control the immune system in vivo.

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DO - 10.1016/j.coi.2006.03.006

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JO - Current Opinion in Immunology

JF - Current Opinion in Immunology

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The role of serine/threonine kinases in T-cell activation

Abstract

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Prizes

Royal Society Dorothy Hodgkin Research Fellowship (2003-2007)

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