The role of tyrosine-9 and the C-terminal helix in the catalytic mechanism of Alpha-class glutathione S-transferases

Keyphrases

• Tyrosine 100%
• Catalytic Mechanism 100%
• Glutathione S-transferase 100%
• 1-chloro-2,4-dinitrobenzene 100%
• C-terminal Helix 100%
• Conformational Change 66%
• Conjugation 66%
• Ethacrynic Acid 66%
• Enzyme Catalysis 33%
• Binding Site 33%
• Thiols 33%
• Phenylalanine 33%
• Substrate Binding 33%
• Catalytic Center 33%
• Truncation 33%
• Drug Metabolism 33%
• Dithiothreitol 33%
• Xenobiotic Metabolism 33%
• Turnover number 33%
• 2-mercaptoethanol 33%
• Hydrophobic Substrates 33%
• Glutathione S-transferase A1 33%
• Truncated Enzyme 33%

Biochemistry, Genetics and Molecular Biology

• Enzyme 100%
• C-Terminus 100%
• Tyrosine 100%
• Catalytic Mechanism 100%
• Glutathione S-Transferase 100%
• Wild Type 50%
• Conformational Change 50%
• Binding Site 25%
• Metabolic Pathway 25%
• Turnover Number 25%
• Dithiothreitol 25%
• 2-Mercaptoethanol 25%
• Glutathione S-Transferase A1 25%
• Thiol 25%
• Phenylalanine 25%