The structure, biosynthesis and function of GPI membrane anchors

Michael A. J. Ferguson

doi:10.1007/978-3-642-60799-8_17

The structure, biosynthesis and function of GPI membrane anchors

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Glycosyl-phosphatidylinositol (GPI) membrane anchors are present in organisms at most stages of eukaryotic evolution, including protozoa, yeast, slime moulds, invertebrates and vertebrates, and are found on a diverse range of proteins. They are primarily responsible for the anchoring of cell-surface proteins in the plasma membrane (or in some cases to the topologically equivalent lumenal surface of secretory vesicles) and may be considered as an alternative to the hydrophobic transmembrane polypeptide anchor of type-1 integral membrane proteins (Fig. 1).

Original language	English
Title of host publication	Molecular mechanisms of signalling and membrane transport
Editors	Karel W. A. Wirtz
Place of Publication	Berlin
Publisher	Springer
Pages	233-245
Number of pages	13
ISBN (Print)	9783642645594, 3540628916
DOIs	https://doi.org/10.1007/978-3-642-60799-8_17
Publication status	Published - 1997
Event	NATO Study Institute on Molecular Mechanisms of Signalling and Targeting Conference - Spetsai, Greece Duration: 18 Aug 1996 → 30 Aug 1996 http://trove.nla.gov.au/version/46516267

Publication series

Name	NATO ASI series. Series H: Cell biology
Publisher	Springer
Volume	101

Conference

Conference	NATO Study Institute on Molecular Mechanisms of Signalling and Targeting Conference
Country/Territory	Greece
City	Spetsai
Period	18/08/96 → 30/08/96
Internet address	http://trove.nla.gov.au/version/46516267

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10.1007/978-3-642-60799-8_17

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title = "The structure, biosynthesis and function of GPI membrane anchors",

abstract = "Glycosyl-phosphatidylinositol (GPI) membrane anchors are present in organisms at most stages of eukaryotic evolution, including protozoa, yeast, slime moulds, invertebrates and vertebrates, and are found on a diverse range of proteins. They are primarily responsible for the anchoring of cell-surface proteins in the plasma membrane (or in some cases to the topologically equivalent lumenal surface of secretory vesicles) and may be considered as an alternative to the hydrophobic transmembrane polypeptide anchor of type-1 integral membrane proteins (Fig. 1).",

author = "Ferguson, {Michael A. J.}",

year = "1997",

doi = "10.1007/978-3-642-60799-8_17",

language = "English",

isbn = "9783642645594",

series = "NATO ASI series. Series H: Cell biology",

publisher = "Springer ",

pages = "233--245",

editor = "{Wirtz }, {Karel W. A.}",

booktitle = "Molecular mechanisms of signalling and membrane transport",

note = "NATO Study Institute on Molecular Mechanisms of Signalling and Targeting Conference ; Conference date: 18-08-1996 Through 30-08-1996",

url = " http://trove.nla.gov.au/version/46516267",

}

Ferguson, MAJ 1997, The structure, biosynthesis and function of GPI membrane anchors. in KWA Wirtz (ed.), Molecular mechanisms of signalling and membrane transport. NATO ASI series. Series H: Cell biology, vol. 101, Springer , Berlin, pp. 233-245, NATO Study Institute on Molecular Mechanisms of Signalling and Targeting Conference, Spetsai, Greece, 18/08/96. https://doi.org/10.1007/978-3-642-60799-8_17

TY - GEN

T1 - The structure, biosynthesis and function of GPI membrane anchors

AU - Ferguson, Michael A. J.

PY - 1997

Y1 - 1997

N2 - Glycosyl-phosphatidylinositol (GPI) membrane anchors are present in organisms at most stages of eukaryotic evolution, including protozoa, yeast, slime moulds, invertebrates and vertebrates, and are found on a diverse range of proteins. They are primarily responsible for the anchoring of cell-surface proteins in the plasma membrane (or in some cases to the topologically equivalent lumenal surface of secretory vesicles) and may be considered as an alternative to the hydrophobic transmembrane polypeptide anchor of type-1 integral membrane proteins (Fig. 1).

AB - Glycosyl-phosphatidylinositol (GPI) membrane anchors are present in organisms at most stages of eukaryotic evolution, including protozoa, yeast, slime moulds, invertebrates and vertebrates, and are found on a diverse range of proteins. They are primarily responsible for the anchoring of cell-surface proteins in the plasma membrane (or in some cases to the topologically equivalent lumenal surface of secretory vesicles) and may be considered as an alternative to the hydrophobic transmembrane polypeptide anchor of type-1 integral membrane proteins (Fig. 1).

U2 - 10.1007/978-3-642-60799-8_17

DO - 10.1007/978-3-642-60799-8_17

M3 - Conference contribution

SN - 9783642645594

SN - 3540628916

T3 - NATO ASI series. Series H: Cell biology

SP - 233

EP - 245

BT - Molecular mechanisms of signalling and membrane transport

A2 - Wirtz , Karel W. A.

PB - Springer

CY - Berlin

T2 - NATO Study Institute on Molecular Mechanisms of Signalling and Targeting Conference

Y2 - 18 August 1996 through 30 August 1996

ER -

The structure, biosynthesis and function of GPI membrane anchors

Abstract

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Conference

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