TY - JOUR
T1 - The SULSA Assay Development Fund
T2 - accelerating translation of new biology from academia to pharma
AU - McElroy, Stuart P.
AU - Jones, Philip S.
AU - Barrault, Denise V.
N1 - SULSA Assay Development Fund was funded through the Scottish Universities Life Sciences Alliance by a grant award from the Scottish Funding Council (SFC Ref: 240599989)
PY - 2017/2
Y1 - 2017/2
N2 - With industry increasingly sourcing preclinical drug discovery projects from academia it is important that new academic discoveries are enabled through translation with HTS-ready assays. However, many scientifically interesting, novel molecular targets lack associated high-quality, robust assays suitable for hit finding and development. To bridge this gap, the Scottish Universities Life Sciences Alliance (SULSA) established a fund to develop assays to meet quality criteria such as those of the European Lead Factory. A diverse project portfolio was quickly assembled, and a review of the learnings and successful outcomes showed this fund as a new highly cost-effective model for leveraging significant follow-on resources, training early-career scientists and establishing a culture of translational drug discovery in the academic community.
AB - With industry increasingly sourcing preclinical drug discovery projects from academia it is important that new academic discoveries are enabled through translation with HTS-ready assays. However, many scientifically interesting, novel molecular targets lack associated high-quality, robust assays suitable for hit finding and development. To bridge this gap, the Scottish Universities Life Sciences Alliance (SULSA) established a fund to develop assays to meet quality criteria such as those of the European Lead Factory. A diverse project portfolio was quickly assembled, and a review of the learnings and successful outcomes showed this fund as a new highly cost-effective model for leveraging significant follow-on resources, training early-career scientists and establishing a culture of translational drug discovery in the academic community.
U2 - 10.1016/j.drudis.2016.09.028
DO - 10.1016/j.drudis.2016.09.028
M3 - Article
C2 - 27720829
VL - 22
SP - 199
EP - 203
JO - Drug Discovery Today
JF - Drug Discovery Today
SN - 1359-6446
IS - 2
ER -