The use of mathematical modelling to describe fluid flow within the colon

A. Timmis, D. J. Smith, R. H. Bridson, M. J. H. Simmons, S. P. Decent

    Research output: Contribution to journalMeeting abstract

    2 Citations (Scopus)

    Abstract

    Very few physical or theoretical models have been developed to assist with product development for oral colonic drug delivery. The aim here is to develop a theoretical mathematical model to describe the geometry of the colon and the fluid flows within it. This is part of a project which aims to predict the distribution and residence time of dosage forms in the colon e.g. whether they will reach the mucosal layer of the colon wall.
    Original languageEnglish
    Pages (from-to)1311-1312
    Number of pages2
    JournalJournal of Pharmacy and Pharmacology
    Volume62
    Issue number10
    DOIs
    Publication statusPublished - Oct 2010

    Cite this

    Timmis, A., Smith, D. J., Bridson, R. H., Simmons, M. J. H., & Decent, S. P. (2010). The use of mathematical modelling to describe fluid flow within the colon. Journal of Pharmacy and Pharmacology, 62(10), 1311-1312. https://doi.org/10.1111/j.2042-7158.2010.01178.x
    Timmis, A. ; Smith, D. J. ; Bridson, R. H. ; Simmons, M. J. H. ; Decent, S. P. / The use of mathematical modelling to describe fluid flow within the colon. In: Journal of Pharmacy and Pharmacology. 2010 ; Vol. 62, No. 10. pp. 1311-1312.
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    abstract = "Very few physical or theoretical models have been developed to assist with product development for oral colonic drug delivery. The aim here is to develop a theoretical mathematical model to describe the geometry of the colon and the fluid flows within it. This is part of a project which aims to predict the distribution and residence time of dosage forms in the colon e.g. whether they will reach the mucosal layer of the colon wall.",
    author = "A. Timmis and Smith, {D. J.} and Bridson, {R. H.} and Simmons, {M. J. H.} and Decent, {S. P.}",
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    Timmis, A, Smith, DJ, Bridson, RH, Simmons, MJH & Decent, SP 2010, 'The use of mathematical modelling to describe fluid flow within the colon', Journal of Pharmacy and Pharmacology, vol. 62, no. 10, pp. 1311-1312. https://doi.org/10.1111/j.2042-7158.2010.01178.x

    The use of mathematical modelling to describe fluid flow within the colon. / Timmis, A.; Smith, D. J.; Bridson, R. H.; Simmons, M. J. H.; Decent, S. P.

    In: Journal of Pharmacy and Pharmacology, Vol. 62, No. 10, 10.2010, p. 1311-1312.

    Research output: Contribution to journalMeeting abstract

    TY - JOUR

    T1 - The use of mathematical modelling to describe fluid flow within the colon

    AU - Timmis, A.

    AU - Smith, D. J.

    AU - Bridson, R. H.

    AU - Simmons, M. J. H.

    AU - Decent, S. P.

    PY - 2010/10

    Y1 - 2010/10

    N2 - Very few physical or theoretical models have been developed to assist with product development for oral colonic drug delivery. The aim here is to develop a theoretical mathematical model to describe the geometry of the colon and the fluid flows within it. This is part of a project which aims to predict the distribution and residence time of dosage forms in the colon e.g. whether they will reach the mucosal layer of the colon wall.

    AB - Very few physical or theoretical models have been developed to assist with product development for oral colonic drug delivery. The aim here is to develop a theoretical mathematical model to describe the geometry of the colon and the fluid flows within it. This is part of a project which aims to predict the distribution and residence time of dosage forms in the colon e.g. whether they will reach the mucosal layer of the colon wall.

    U2 - 10.1111/j.2042-7158.2010.01178.x

    DO - 10.1111/j.2042-7158.2010.01178.x

    M3 - Meeting abstract

    VL - 62

    SP - 1311

    EP - 1312

    JO - Journal of Pharmacy and Pharmacology

    JF - Journal of Pharmacy and Pharmacology

    SN - 0022-3573

    IS - 10

    ER -