The use of mathematical modelling to describe fluid flow within the colon

A. Timmis; D. J. Smith; R. H. Bridson; M. J. H. Simmons; S. P. Decent

doi:10.1111/j.2042-7158.2010.01178.x

The use of mathematical modelling to describe fluid flow within the colon

A. Timmis, D. J. Smith, R. H. Bridson, M. J. H. Simmons, S. P. Decent

Research output: Contribution to journal › Meeting abstract › peer-review

3 Citations (Scopus)

Abstract

Very few physical or theoretical models have been developed to assist with product development for oral colonic drug delivery. The aim here is to develop a theoretical mathematical model to describe the geometry of the colon and the fluid flows within it. This is part of a project which aims to predict the distribution and residence time of dosage forms in the colon e.g. whether they will reach the mucosal layer of the colon wall.

Original language	English
Pages (from-to)	1311-1312
Number of pages	2
Journal	Journal of Pharmacy and Pharmacology
Volume	62
Issue number	10
DOIs	https://doi.org/10.1111/j.2042-7158.2010.01178.x
Publication status	Published - Oct 2010

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10.1111/j.2042-7158.2010.01178.x

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title = "The use of mathematical modelling to describe fluid flow within the colon",

abstract = "Very few physical or theoretical models have been developed to assist with product development for oral colonic drug delivery. The aim here is to develop a theoretical mathematical model to describe the geometry of the colon and the fluid flows within it. This is part of a project which aims to predict the distribution and residence time of dosage forms in the colon e.g. whether they will reach the mucosal layer of the colon wall.",

author = "A. Timmis and Smith, {D. J.} and Bridson, {R. H.} and Simmons, {M. J. H.} and Decent, {S. P.}",

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AU - Timmis, A.

AU - Smith, D. J.

AU - Bridson, R. H.

AU - Simmons, M. J. H.

AU - Decent, S. P.

PY - 2010/10

Y1 - 2010/10

N2 - Very few physical or theoretical models have been developed to assist with product development for oral colonic drug delivery. The aim here is to develop a theoretical mathematical model to describe the geometry of the colon and the fluid flows within it. This is part of a project which aims to predict the distribution and residence time of dosage forms in the colon e.g. whether they will reach the mucosal layer of the colon wall.

AB - Very few physical or theoretical models have been developed to assist with product development for oral colonic drug delivery. The aim here is to develop a theoretical mathematical model to describe the geometry of the colon and the fluid flows within it. This is part of a project which aims to predict the distribution and residence time of dosage forms in the colon e.g. whether they will reach the mucosal layer of the colon wall.

U2 - 10.1111/j.2042-7158.2010.01178.x

DO - 10.1111/j.2042-7158.2010.01178.x

M3 - Meeting abstract

C2 - 20840162

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VL - 62

SP - 1311

EP - 1312

JO - Journal of Pharmacy and Pharmacology

JF - Journal of Pharmacy and Pharmacology

IS - 10

ER -

The use of mathematical modelling to describe fluid flow within the colon

Abstract

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