The use of transgenic animals to assess the role of metabolism in target organ toxicity

Keyphrases

• Absorption Distribution 50%
• Bacterial System 50%
• Biological Effects 50%
• Biological Role 50%
• Chemical Carcinogenesis 50%
• Cytochrome P450 (CYP450) 50%
• Drug Disposition 50%
• Drug Metabolism 50%
• Drug-metabolizing Enzymes 50%
• Gene Expression 50%
• In Vitro Model 50%
• In Vivo Model 50%
• Mammalian System 50%
• Metabolism 100%
• Physiologically Relevant Conditions 50%
• Target Organ Toxicity 100%
• Transgenic Animals 100%
• Yeast System 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Chemical Carcinogenesis 50%
• Cytochrome 50%
• Drug Metabolism 50%
• Drug Metabolizing Enzyme 50%
• Organ Toxicity 100%
• Transgenic Animal 100%