The white blood cell and peripheral arterial disease

P. Hickman; J. J. Belch

The white blood cell and peripheral arterial disease

P. Hickman
, J. J. Belch

Research output: Contribution to journal › Article › peer-review

Abstract

Peripheral arterial obstructive disease (PAOD) is a common cause of morbidity in middle aged men with 5% of men, over 50 years, suffering from intermittent claudication. Claudication itself does not cause death but claudicants have a mortality three times that expected, mainly from cardiovascular disease. The white blood cell has recently been implicated in the pathogenesis of PAOD. This article will examine the evidence for the involvement of the neutrophil in this increased mortality and describe the possible pathogenesis. It is possible that treatment of claudication could modify white cell responses, reducing subsequent mortality and morbidity.

Original language	English
Pages (from-to)	40-47
Number of pages	8
Journal	International Angiology
Volume	13
Issue number	1
Publication status	Published - 1994

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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http://www.ncbi.nlm.nih.gov/pubmed/8077796

Cite this

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title = "The white blood cell and peripheral arterial disease",

abstract = "Peripheral arterial obstructive disease (PAOD) is a common cause of morbidity in middle aged men with 5\% of men, over 50 years, suffering from intermittent claudication. Claudication itself does not cause death but claudicants have a mortality three times that expected, mainly from cardiovascular disease. The white blood cell has recently been implicated in the pathogenesis of PAOD. This article will examine the evidence for the involvement of the neutrophil in this increased mortality and describe the possible pathogenesis. It is possible that treatment of claudication could modify white cell responses, reducing subsequent mortality and morbidity.",

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AU - Hickman, P.

AU - Belch, J. J.

PY - 1994

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N2 - Peripheral arterial obstructive disease (PAOD) is a common cause of morbidity in middle aged men with 5% of men, over 50 years, suffering from intermittent claudication. Claudication itself does not cause death but claudicants have a mortality three times that expected, mainly from cardiovascular disease. The white blood cell has recently been implicated in the pathogenesis of PAOD. This article will examine the evidence for the involvement of the neutrophil in this increased mortality and describe the possible pathogenesis. It is possible that treatment of claudication could modify white cell responses, reducing subsequent mortality and morbidity.

AB - Peripheral arterial obstructive disease (PAOD) is a common cause of morbidity in middle aged men with 5% of men, over 50 years, suffering from intermittent claudication. Claudication itself does not cause death but claudicants have a mortality three times that expected, mainly from cardiovascular disease. The white blood cell has recently been implicated in the pathogenesis of PAOD. This article will examine the evidence for the involvement of the neutrophil in this increased mortality and describe the possible pathogenesis. It is possible that treatment of claudication could modify white cell responses, reducing subsequent mortality and morbidity.

M3 - Article

SN - 0392-9590

VL - 13

SP - 40

EP - 47

JO - International Angiology

JF - International Angiology

IS - 1

ER -

The white blood cell and peripheral arterial disease

Abstract

UN SDGs

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