The zig-zag-zig in oomycete-plant interactions

Ingo Hein, Eleanor M. Gilroy, Miles R. Armstrong, Paul R. J. Birch

    Research output: Contribution to journalReview article

    92 Citations (Scopus)

    Abstract

    In addition to a range of preformed barriers, plants defend themselves against microbial invasion by detecting conserved, secreted molecules, called pathogen-associated molecular patterns (PAMPs). PAMP-triggered immunity (PTI) is the first inducible layer of plant defence that microbial pathogens must navigate by the delivery of effector proteins that act to suppress or otherwise manipulate key components of resistance. Effectors may themselves be targeted by a further layer of defence, effector-triggered immunity (ETI), as their presence inside or outside host cells may be detected by resistance proteins. This 'zig-zag-zig' of tightly co-evolving molecular interactions determines the outcome of attempted infection. In this article, we consider the complex molecular interplay between plants and plant pathogenic oomycetes, drawing on recent literature to illustrate what is known about oomycete PAMPs and elicitors of defence responses, the effectors they utilize to suppress PTI, and the phenomenal molecular 'battle' between effector and resistance (R) genes that dictates the establishment or evasion of ETI.

    Original languageEnglish
    Pages (from-to)547-562
    Number of pages16
    JournalMolecular Plant Pathology
    Volume10
    Issue number4
    DOIs
    Publication statusPublished - Jul 2009

    Keywords

    • DOWNY MILDEW RESISTANCE
    • INF1-INDUCED CELL-DEATH
    • PARASITICA VAR.-NICOTIANAE
    • BROAD-SPECTRUM RESISTANCE
    • CELLULOSE-BINDING DOMAINS
    • EXPRESSED SEQUENCE TAGS
    • LATE BLIGHT RESISTANCE
    • SOJAE-EFFECTOR AVR1B
    • FOR-GENE CONCEPT
    • NB-LRR GENES

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