Projects per year
Ischemic heart disease (IHD) is one of the primary causes of death around the world. Therapeutic angiogenesis is a promising innovative approach for treating IHD, improving cardiac function by promoting blood perfusion to the ischemic myocardium. This treatment is especially important for targeting patients that are unable to undergo angioplasty or bypass surgery. Chinese herbal medicines have been used for more than 2,500 years and they play an important role alongside contemporary medicines in China. Growing evidence in animal models show Chinese herbal medicines can provide therapeutic effect on IHD by targeting angiogenesis. Identifying the mechanism in which Chinese herbal medicines can promote angiogenesis in IHD is a major topic in the field of traditional Chinese medicine, and has the potential for advancing therapeutic treatment. This review summarizes the progression of research and highlights potential pro-angiogenic mechanisms of Chinese herbal medicines in IHD. In addition, an outline of the limitations of Chinese herbal medicines and challenges they face will be presented.
|Journal||Frontiers in Pharmacology|
|Publication status||Published - 26 Apr 2018|
- ischemic heart disease
- treatment status
- Chinese herbal medicines
- therapeutic angiogenesis
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- 1 Finished
Innovation in modelling Placenta for Maternal and Fetal Health (iPLACENTA) (joint with Aston University, Mimetas BV, St George's Medical School, University College Cork, Universita Degli Studi di Torino, Institut National de le Sante et de la Recherche Medicale, Universitaet Rostock, Fundacion Para le Investigacion del Hospital Universitario La Fe De La Comunidad Valencia, Katholieke Universiteit Leuven, Universiteit Maastricht)
COMMISSION OF THE EUROPEAN COMMUNITIES
1/03/18 → 31/05/22