Therapeutic mammaplasty

Extending indications and achieving low incomplete excision rates

M. V. Schaverien, C. Raine, E. Majdak-Paredes, J. M. Dixon

    Research output: Contribution to journalArticle

    11 Citations (Scopus)

    Abstract

    Aims: The aim of this study was to report the outcomes of the first 50 consecutive therapeutic mammaplasty procedures at the Edinburgh Breast Unit.

    Methods: A retrospective case-notes analysis was performed. In addition a validated patient satisfaction and outcomes questionnaire was sent to all patients.

    Results: Fifty therapeutic mammaplasty procedures were performed in 48 patients, with contralateral synchronous breast reduction performed in 42 of these patients. The median age was 58 years (range, 34-81). The median total tumour size was 28 mm (range, 7-83 mm) and 11 patients had multifocal tumours. The median wide local excision weight was 119 g (range, 15-815) and the median total excision weight was 354 g (range, 20-1725). Neoadjuvant letrozole was used in 16 patients and neoadjuvant chemotherapy was given in six. Incomplete excision (DCIS) occurred in only one patient who underwent reexcision. Complications occurred in 19 breasts overall, delaying adjuvant chemotherapy in one patient. Median reported patient satisfaction with appearance was 9.5 out of ten, with 33 of 35 respondents reporting that they definitely or probably would choose the same operation again.

    Conclusions: Therapeutic mammaplasty can be performed with a low rate of incomplete excision and complications, and high patient satisfaction, even with large tumours and multifocal disease. In this study the use of neoadjuvant letrozole in selected oestrogen receptor positive tumours, intraoperative radiographic imaging of specimens, and targeting further excision to around the tumour bed, was associated with a very low rate of incomplete excision. (C) 2013 Elsevier Ltd. All rights reserved.

    Original languageEnglish
    Pages (from-to)329-333
    Number of pages5
    JournalEuropean Journal of Surgical Oncology
    Volume39
    Issue number4
    DOIs
    Publication statusPublished - 2013

    Keywords

    • Therapeutic mammaplasties
    • TRIAL
    • Cosmesis
    • 20-YEAR FOLLOW-UP
    • CANCER
    • Oncoplastic breast surgery
    • OUTCOMES
    • MASTECTOMY
    • Breast conserving surgery
    • BREAST-CONSERVING SURGERY
    • REDUCTION
    • ONCOPLASTIC SURGERY
    • Margins breast cancer
    • LETROZOLE

    Cite this

    Schaverien, M. V. ; Raine, C. ; Majdak-Paredes, E. ; Dixon, J. M. / Therapeutic mammaplasty : Extending indications and achieving low incomplete excision rates. In: European Journal of Surgical Oncology. 2013 ; Vol. 39, No. 4. pp. 329-333.
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    title = "Therapeutic mammaplasty: Extending indications and achieving low incomplete excision rates",
    abstract = "Aims: The aim of this study was to report the outcomes of the first 50 consecutive therapeutic mammaplasty procedures at the Edinburgh Breast Unit.Methods: A retrospective case-notes analysis was performed. In addition a validated patient satisfaction and outcomes questionnaire was sent to all patients.Results: Fifty therapeutic mammaplasty procedures were performed in 48 patients, with contralateral synchronous breast reduction performed in 42 of these patients. The median age was 58 years (range, 34-81). The median total tumour size was 28 mm (range, 7-83 mm) and 11 patients had multifocal tumours. The median wide local excision weight was 119 g (range, 15-815) and the median total excision weight was 354 g (range, 20-1725). Neoadjuvant letrozole was used in 16 patients and neoadjuvant chemotherapy was given in six. Incomplete excision (DCIS) occurred in only one patient who underwent reexcision. Complications occurred in 19 breasts overall, delaying adjuvant chemotherapy in one patient. Median reported patient satisfaction with appearance was 9.5 out of ten, with 33 of 35 respondents reporting that they definitely or probably would choose the same operation again.Conclusions: Therapeutic mammaplasty can be performed with a low rate of incomplete excision and complications, and high patient satisfaction, even with large tumours and multifocal disease. In this study the use of neoadjuvant letrozole in selected oestrogen receptor positive tumours, intraoperative radiographic imaging of specimens, and targeting further excision to around the tumour bed, was associated with a very low rate of incomplete excision. (C) 2013 Elsevier Ltd. All rights reserved.",
    keywords = "Therapeutic mammaplasties, TRIAL, Cosmesis, 20-YEAR FOLLOW-UP, CANCER, Oncoplastic breast surgery, OUTCOMES, MASTECTOMY, Breast conserving surgery, BREAST-CONSERVING SURGERY, REDUCTION, ONCOPLASTIC SURGERY, Margins breast cancer, LETROZOLE",
    author = "Schaverien, {M. V.} and C. Raine and E. Majdak-Paredes and Dixon, {J. M.}",
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    Therapeutic mammaplasty : Extending indications and achieving low incomplete excision rates. / Schaverien, M. V.; Raine, C.; Majdak-Paredes, E.; Dixon, J. M.

    In: European Journal of Surgical Oncology, Vol. 39, No. 4, 2013, p. 329-333.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Therapeutic mammaplasty

    T2 - Extending indications and achieving low incomplete excision rates

    AU - Schaverien, M. V.

    AU - Raine, C.

    AU - Majdak-Paredes, E.

    AU - Dixon, J. M.

    PY - 2013

    Y1 - 2013

    N2 - Aims: The aim of this study was to report the outcomes of the first 50 consecutive therapeutic mammaplasty procedures at the Edinburgh Breast Unit.Methods: A retrospective case-notes analysis was performed. In addition a validated patient satisfaction and outcomes questionnaire was sent to all patients.Results: Fifty therapeutic mammaplasty procedures were performed in 48 patients, with contralateral synchronous breast reduction performed in 42 of these patients. The median age was 58 years (range, 34-81). The median total tumour size was 28 mm (range, 7-83 mm) and 11 patients had multifocal tumours. The median wide local excision weight was 119 g (range, 15-815) and the median total excision weight was 354 g (range, 20-1725). Neoadjuvant letrozole was used in 16 patients and neoadjuvant chemotherapy was given in six. Incomplete excision (DCIS) occurred in only one patient who underwent reexcision. Complications occurred in 19 breasts overall, delaying adjuvant chemotherapy in one patient. Median reported patient satisfaction with appearance was 9.5 out of ten, with 33 of 35 respondents reporting that they definitely or probably would choose the same operation again.Conclusions: Therapeutic mammaplasty can be performed with a low rate of incomplete excision and complications, and high patient satisfaction, even with large tumours and multifocal disease. In this study the use of neoadjuvant letrozole in selected oestrogen receptor positive tumours, intraoperative radiographic imaging of specimens, and targeting further excision to around the tumour bed, was associated with a very low rate of incomplete excision. (C) 2013 Elsevier Ltd. All rights reserved.

    AB - Aims: The aim of this study was to report the outcomes of the first 50 consecutive therapeutic mammaplasty procedures at the Edinburgh Breast Unit.Methods: A retrospective case-notes analysis was performed. In addition a validated patient satisfaction and outcomes questionnaire was sent to all patients.Results: Fifty therapeutic mammaplasty procedures were performed in 48 patients, with contralateral synchronous breast reduction performed in 42 of these patients. The median age was 58 years (range, 34-81). The median total tumour size was 28 mm (range, 7-83 mm) and 11 patients had multifocal tumours. The median wide local excision weight was 119 g (range, 15-815) and the median total excision weight was 354 g (range, 20-1725). Neoadjuvant letrozole was used in 16 patients and neoadjuvant chemotherapy was given in six. Incomplete excision (DCIS) occurred in only one patient who underwent reexcision. Complications occurred in 19 breasts overall, delaying adjuvant chemotherapy in one patient. Median reported patient satisfaction with appearance was 9.5 out of ten, with 33 of 35 respondents reporting that they definitely or probably would choose the same operation again.Conclusions: Therapeutic mammaplasty can be performed with a low rate of incomplete excision and complications, and high patient satisfaction, even with large tumours and multifocal disease. In this study the use of neoadjuvant letrozole in selected oestrogen receptor positive tumours, intraoperative radiographic imaging of specimens, and targeting further excision to around the tumour bed, was associated with a very low rate of incomplete excision. (C) 2013 Elsevier Ltd. All rights reserved.

    KW - Therapeutic mammaplasties

    KW - TRIAL

    KW - Cosmesis

    KW - 20-YEAR FOLLOW-UP

    KW - CANCER

    KW - Oncoplastic breast surgery

    KW - OUTCOMES

    KW - MASTECTOMY

    KW - Breast conserving surgery

    KW - BREAST-CONSERVING SURGERY

    KW - REDUCTION

    KW - ONCOPLASTIC SURGERY

    KW - Margins breast cancer

    KW - LETROZOLE

    U2 - 10.1016/j.ejso.2013.01.006

    DO - 10.1016/j.ejso.2013.01.006

    M3 - Article

    VL - 39

    SP - 329

    EP - 333

    JO - European Journal of Surgical Oncology

    JF - European Journal of Surgical Oncology

    SN - 0748-7983

    IS - 4

    ER -