Towards monodisperse microbubble populations via microfluidic chip flow-focusing

Yaoyao Cui, Paul A. Campbell

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    6 Citations (Scopus)

    Abstract

    Encapsulated ultrasound contrast agents (UCA) have received considerable attention recently, not only because of their echogenic properties which aid diagnostic imaging, but also for their ability to mediate targeted drug and gene delivery. Certain advantages may arise if monodisperse populations of microbubbles can be developed: specifically, an abrupt, well controlled response may be achievable which would lend itself to enhanced delivery efficiencies. In this paper, we highlight the rationale for the development of our own in-house approach to microbubble generation, and set this in the context of some contemporary bubble preparation technologies based on microfludic methods.

    Original languageEnglish
    Title of host publication2008 IEEE Ultrasonics Symposium, Vols 1-4 and Appendix
    Place of PublicationNEW YORK
    PublisherIEEE Computer Society
    Pages1663-1666
    Number of pages4
    ISBN (Print)978-1-4244-2428-3
    DOIs
    Publication statusPublished - 2008
    Event2008 IEEE International Ultrasonics Symposium (IUS) - Beijing, China
    Duration: 2 Nov 20085 Nov 2008
    http://ewh.ieee.org/conf/ius_2008/

    Conference

    Conference2008 IEEE International Ultrasonics Symposium (IUS)
    Abbreviated title2008 IEEE IUS
    CountryChina
    CityBeijing
    Period2/11/085/11/08
    Internet address

    Keywords

    • Microbubble
    • flow-focusing
    • microfludics
    • medical ultrasound therapy
    • COAXIAL ELECTROHYDRODYNAMIC ATOMIZATION
    • COATED MICROBUBBLES
    • CONTRAST AGENTS
    • BUBBLES
    • DEVICE

    Cite this

    Cui, Y., & Campbell, P. A. (2008). Towards monodisperse microbubble populations via microfluidic chip flow-focusing. In 2008 IEEE Ultrasonics Symposium, Vols 1-4 and Appendix (pp. 1663-1666). IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2008.0406