Transfusion-induced, Fc gamma-receptor-blocking antibodies: spectrum of cellular reactivity

M. A. Forwell, M. G. Peel, K. S. Froebel, J. J. Belch, R. N. MacSween, G. P. Sandilands

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    14 Citations (Scopus)


    In this study we have shown that transfusion-induced Fc gamma R-blocking antibodies have the capacity to react with various cell types which are known to possess this receptor i.e., lymphocytes (T and B cells), polymorphs and platelets. In contrast we were unable to demonstrate any reactivity with K (or NK) lymphocytes or with monocytes. The spectrum of cellular reactivity exhibited by these antibodies suggests that their effect on the immune system may be complex.
    Original languageEnglish
    Pages (from-to)63-67
    Number of pages5
    JournalJournal of Clinical & Laboratory Immunology
    Issue number2
    Publication statusPublished - 1986


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