Treatment of oral dysplasia with 5% imiquimod cream: Short communication

R. Mullins (Lead / Corresponding author), M. Ansell, S. Laverick

    Research output: Contribution to journalArticlepeer-review

    Abstract

    We report what we think is the first treatment of oral dysplasia with 5% imiquimod cream. A 60-year-old man presented with varying degrees of dysplasia on the soft palate. A cover plate was fabricated and the patient was prescribed 5% imiquimod cream, a topical imunomodulator, for six weeks. The lesion improved and histological examination of an incisional biopsy found no features of dysplasia. This case highlights the efficacy of imiquimod cream in the treatment of dysplasia, and the need for development of a preparation suitable for the oral mucosa.

    Original languageEnglish
    Pages (from-to)1028-1029
    Number of pages2
    JournalBritish Journal of Oral and Maxillofacial Surgery
    Volume54
    Issue number9
    Early online date10 May 2016
    DOIs
    Publication statusPublished - Nov 2016

    Keywords

    • Coverplate
    • Imiquimod
    • Non-surgical management
    • Oral dysplasia

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