Treatment of oral dysplasia with 5% imiquimod cream: Short communication

R. Mullins; M. Ansell; S. Laverick

doi:10.1016/j.bjoms.2016.01.030

Treatment of oral dysplasia with 5% imiquimod cream: Short communication

R. Mullins (Lead / Corresponding author), M. Ansell, S. Laverick

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

We report what we think is the first treatment of oral dysplasia with 5% imiquimod cream. A 60-year-old man presented with varying degrees of dysplasia on the soft palate. A cover plate was fabricated and the patient was prescribed 5% imiquimod cream, a topical imunomodulator, for six weeks. The lesion improved and histological examination of an incisional biopsy found no features of dysplasia. This case highlights the efficacy of imiquimod cream in the treatment of dysplasia, and the need for development of a preparation suitable for the oral mucosa.

Original language	English
Pages (from-to)	1028-1029
Number of pages	2
Journal	British Journal of Oral and Maxillofacial Surgery
Volume	54
Issue number	9
Early online date	10 May 2016
DOIs	https://doi.org/10.1016/j.bjoms.2016.01.030
Publication status	Published - Nov 2016

Keywords

Coverplate
Imiquimod
Non-surgical management
Oral dysplasia

ASJC Scopus subject areas

Oral Surgery
Otorhinolaryngology
Surgery

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10.1016/j.bjoms.2016.01.030

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abstract = "We report what we think is the first treatment of oral dysplasia with 5% imiquimod cream. A 60-year-old man presented with varying degrees of dysplasia on the soft palate. A cover plate was fabricated and the patient was prescribed 5% imiquimod cream, a topical imunomodulator, for six weeks. The lesion improved and histological examination of an incisional biopsy found no features of dysplasia. This case highlights the efficacy of imiquimod cream in the treatment of dysplasia, and the need for development of a preparation suitable for the oral mucosa.",

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AU - Ansell, M.

AU - Laverick, S.

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AB - We report what we think is the first treatment of oral dysplasia with 5% imiquimod cream. A 60-year-old man presented with varying degrees of dysplasia on the soft palate. A cover plate was fabricated and the patient was prescribed 5% imiquimod cream, a topical imunomodulator, for six weeks. The lesion improved and histological examination of an incisional biopsy found no features of dysplasia. This case highlights the efficacy of imiquimod cream in the treatment of dysplasia, and the need for development of a preparation suitable for the oral mucosa.

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KW - Imiquimod

KW - Non-surgical management

KW - Oral dysplasia

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ER -

Treatment of oral dysplasia with 5% imiquimod cream: Short communication

Abstract

Keywords

ASJC Scopus subject areas

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