Tricuspid annular disjunction can be isolated and even arrhythmogenic. A cardiac magnetic resonance study

Francesco Mangini (Lead / Corresponding author), Eluisa Muscogiuri, Roberto Del Villano, Roberto Rosato, Grazia Casavecchia, Filippo Pigazzani, Elvira Bruno, Antonio Medico, Massimo Grimaldi, Robert W. W. Biederman

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Abstract

Mitral annular disjunction is related to increased arrhythmogenic risk; in a certain percentage of cases, mitral annular disjunction is associated with tricuspid annular disjunction. While the prognostic implications of mitral annular disjunction have been well established, there is still little data to define this aspect regarding the tricuspid annular disjunction. We present a case of a patient admitted for life-threatening ventricular arrhythmias that occurred during endurance sporting activity, who was found to have isolated tricuspid annular disjunction, not associated with mitral annular disjunction. Based on several factors, including the morphology and axis of QRS of the ventricular arrhythmic activity, and its behavior, including the response to antiarrhythmic treatment, and in keeping with the finding of edema and late gadolinium enhancement at the basal segment of the right ventricle free wall on cardiac magnetic resonance imaging, a direct relation between tricuspid annular disjunction and ventricular arrhythmias was highly conceivable. Control after three months showed almost complete remission of the previously described and persistence of LGE at the level of the basal segment of the free wall of the right ventricle, so giving strength to the hypothesis of an event related to increased acute RV free wall stress, secondary to high-intensity physical activity, established on a framework of chronic wall stress, as represented by LGE, similarly to what happens for mitral valve prolapse. To the best of our knowledge, this is the first case of a legitimately conceivable direct relation between tricuspid annular disjunction and ventricular arrhythmias.

Original languageEnglish
Pages (from-to)41-49
Number of pages9
JournalArchive of Clinical Cases
Volume9
Issue number2
DOIs
Publication statusPublished - Apr 2022

Keywords

  • tricuspid valve prolapse
  • tricuspid annular disjunction
  • mitral valve prolapse
  • mitral annular disjunction
  • ventricular arrhythmias
  • endurance exercise activity
  • cardiac magnetic resonance imaging

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