Two mobile Pectobacterium atrosepticum prophages modulate virulence

Terry J. Evans, Sarah J. Coulthurst, Evangelia Komitopoulou, George P. C. Salmond

    Research output: Contribution to journalArticlepeer-review

    11 Citations (Scopus)

    Abstract

    The Pectobacterium atrosepticum strain SCRI1043 genome contains two complete prophage sequences. One, ECA41, is Mu-like and is able to integrate into, and excise from, various genomic locations. The other, ECA29, is a P2 family prophage, and is also able to excise from the genome. Excision of both prophages is rare and we were unable to induce lysis of cultures. Deletion of the entire prophages, both separately and in combination, did not affect the growth rate or the secretion of plant cell wall-degrading enzymes, but swimming motility was decreased. The virulence of prophage deletion strains in the potato host was decreased.

    Original languageEnglish
    Pages (from-to)195-202
    Number of pages8
    JournalFEMS Microbiology Letters
    Volume304
    Issue number2
    DOIs
    Publication statusPublished - Mar 2010

    Keywords

    • Erwinia
    • Pectobacterium atrosepticum
    • prophages
    • horizontally acquired islands
    • potato
    • virulence
    • CAROTOVORA SUBSP-ATROSEPTICA
    • ERWINIA-CAROTOVORA
    • ENTERIC PHYTOPATHOGEN
    • BACTERIAL VIRULENCE
    • SALMONELLA-ENTERICA
    • REDUCED VIRULENCE
    • TOXIN
    • IDENTIFICATION
    • PATHOGEN
    • BACTERIOPHAGES

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