Unlocking the chromatin code by deciphering protein–DNA interactions

Dalila Bensaddek, Angus Lamond (Lead / Corresponding author)

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Abstract

Characterizing the composition of protein complexes bound to different genomic loci is essential for advancing our mechanistic understanding of transcriptional regulation. In their recent study, Krijgsveld and colleagues (Rafiee et al, 2016) report ChIP-SICAP, a powerful tool for deciphering the chromatin proteome by combining chromatin immunoprecipitation, selective isolation of chromatin-associated proteins and mass spectrometry.
Original languageEnglish
Article number887
Pages (from-to)1-3
Number of pages3
JournalMolecular Systems Biology
Volume12
Issue number11
Early online date10 Nov 2016
DOIs
Publication statusPublished - Nov 2016

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