Unlocking the chromatin code by deciphering protein–DNA interactions

Dalila Bensaddek; Angus Lamond

doi:10.15252/msb.20167332

Unlocking the chromatin code by deciphering protein–DNA interactions

Dalila Bensaddek, Angus Lamond (Lead / Corresponding author)

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Abstract

Characterizing the composition of protein complexes bound to different genomic loci is essential for advancing our mechanistic understanding of transcriptional regulation. In their recent study, Krijgsveld and colleagues (Rafiee et al, 2016) report ChIP-SICAP, a powerful tool for deciphering the chromatin proteome by combining chromatin immunoprecipitation, selective isolation of chromatin-associated proteins and mass spectrometry.

Original language	English
Article number	887
Pages (from-to)	1-3
Number of pages	3
Journal	Molecular Systems Biology
Volume	12
Issue number	11
Early online date	10 Nov 2016
DOIs	https://doi.org/10.15252/msb.20167332
Publication status	Published - Nov 2016

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10.15252/msb.20167332Licence: CC BY

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Copyright 2016 The Authors. This is an open access article under the terms of the Creative Commons Attribution 4.0 License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Final published version, 326 KBLicence: CC BY

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abstract = "Characterizing the composition of protein complexes bound to different genomic loci is essential for advancing our mechanistic understanding of transcriptional regulation. In their recent study, Krijgsveld and colleagues (Rafiee et al, 2016) report ChIP-SICAP, a powerful tool for deciphering the chromatin proteome by combining chromatin immunoprecipitation, selective isolation of chromatin-associated proteins and mass spectrometry.",

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Unlocking the chromatin code by deciphering protein–DNA interactions

Abstract

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