TY - JOUR
T1 - Upconversion nanoparticles as a contrast agent for photoacoustic imaging in live mice
AU - Maji, Swarup Kumar
AU - Sreejith, Sivaramapanicker
AU - Joseph, James
AU - Lin, Manjing
AU - He, Tingchao
AU - Tong, Yan
AU - Sun, Handong
AU - Yu, Sidney Wing Kwong
AU - Zhao, Yanli
PY - 2014/8/27
Y1 - 2014/8/27
N2 - An inclusion complex of NaYF4:Yb3+,Er3+ upconversion nanoparticles with α-cyclodextrin in aqueous conditions exhibits luminescence quenching when excited at 980 nm. This non-radiative relaxation leads to an unprecedented photoacoustic signal enhancement. In vivo localization of α-cyclodextrin-covered NaYF4:Yb 3+,Er3+ is demonstrated using photoacoustic tomography in live mice, showing its high capability for photoacoustic imaging.
AB - An inclusion complex of NaYF4:Yb3+,Er3+ upconversion nanoparticles with α-cyclodextrin in aqueous conditions exhibits luminescence quenching when excited at 980 nm. This non-radiative relaxation leads to an unprecedented photoacoustic signal enhancement. In vivo localization of α-cyclodextrin-covered NaYF4:Yb 3+,Er3+ is demonstrated using photoacoustic tomography in live mice, showing its high capability for photoacoustic imaging.
KW - contrast agent
KW - live mice
KW - photoacoustic imaging
KW - upconversion nanoparticles
UR - http://www.scopus.com/inward/record.url?scp=84906783536&partnerID=8YFLogxK
U2 - 10.1002/adma.201400831
DO - 10.1002/adma.201400831
M3 - Article
C2 - 24913756
AN - SCOPUS:84906783536
VL - 26
SP - 5633
EP - 5638
JO - Journal of Optoelectronics and Advanced Materials
JF - Journal of Optoelectronics and Advanced Materials
SN - 1454-4164
IS - 32
ER -
