Verrucous carcinoma arising in pseudoepitheliomatous keratotic and micaceous balanitis, without evidence of human papillomavirus

F. J. Child, B. K. Kim, R. Ganesan, S. A. Southern, C. S. Herrington, E. Calonje

    Research output: Contribution to journalArticle

    20 Citations (Scopus)

    Abstract

    Pseudoepitheliomatous keratotic and micaceous balanitis (PKMB) is a condition which occurs on the glans penis of older men and may be associated with the development of a verrucous carcinoma. A role for human papillomavirus (HPV) in the aetiology of verrucous carcinoma has been implicated and several different HPV types have been found. We report a 74-year-old man who developed a verrucous carcinoma within an area of PKMB on the glans penis. Using a broad-spectrum polymerase chain reaction technique for identifying HPV, the epidermis of the area of PKMB and of the verrucous carcinoma were examined and no HPV DNA was identifiable. These results suggest that there is no part for HPV in the pathogenesis of PKMB or its transformation to verrucous carcinoma.

    Original languageEnglish
    Pages (from-to)183-187
    Number of pages5
    JournalBritish Journal of Dermatology
    Volume143
    Issue number1
    DOIs
    Publication statusPublished - 2000

    Cite this

    Child, F. J. ; Kim, B. K. ; Ganesan, R. ; Southern, S. A. ; Herrington, C. S. ; Calonje, E. . / Verrucous carcinoma arising in pseudoepitheliomatous keratotic and micaceous balanitis, without evidence of human papillomavirus. In: British Journal of Dermatology. 2000 ; Vol. 143, No. 1. pp. 183-187.
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    title = "Verrucous carcinoma arising in pseudoepitheliomatous keratotic and micaceous balanitis, without evidence of human papillomavirus",
    abstract = "Pseudoepitheliomatous keratotic and micaceous balanitis (PKMB) is a condition which occurs on the glans penis of older men and may be associated with the development of a verrucous carcinoma. A role for human papillomavirus (HPV) in the aetiology of verrucous carcinoma has been implicated and several different HPV types have been found. We report a 74-year-old man who developed a verrucous carcinoma within an area of PKMB on the glans penis. Using a broad-spectrum polymerase chain reaction technique for identifying HPV, the epidermis of the area of PKMB and of the verrucous carcinoma were examined and no HPV DNA was identifiable. These results suggest that there is no part for HPV in the pathogenesis of PKMB or its transformation to verrucous carcinoma.",
    author = "Child, {F. J.} and Kim, {B. K.} and R. Ganesan and Southern, {S. A.} and Herrington, {C. S.} and E. Calonje",
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    Verrucous carcinoma arising in pseudoepitheliomatous keratotic and micaceous balanitis, without evidence of human papillomavirus. / Child, F. J. ; Kim, B. K.; Ganesan, R. ; Southern, S. A. ; Herrington, C. S. ; Calonje, E. .

    In: British Journal of Dermatology, Vol. 143, No. 1, 2000, p. 183-187.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Verrucous carcinoma arising in pseudoepitheliomatous keratotic and micaceous balanitis, without evidence of human papillomavirus

    AU - Child, F. J.

    AU - Kim, B. K.

    AU - Ganesan, R.

    AU - Southern, S. A.

    AU - Herrington, C. S.

    AU - Calonje, E.

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    AB - Pseudoepitheliomatous keratotic and micaceous balanitis (PKMB) is a condition which occurs on the glans penis of older men and may be associated with the development of a verrucous carcinoma. A role for human papillomavirus (HPV) in the aetiology of verrucous carcinoma has been implicated and several different HPV types have been found. We report a 74-year-old man who developed a verrucous carcinoma within an area of PKMB on the glans penis. Using a broad-spectrum polymerase chain reaction technique for identifying HPV, the epidermis of the area of PKMB and of the verrucous carcinoma were examined and no HPV DNA was identifiable. These results suggest that there is no part for HPV in the pathogenesis of PKMB or its transformation to verrucous carcinoma.

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    DO - 10.1046/j.1365-2133.2000.03613.x

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