Villoglandular adenocarcinoma of the cervix: clarity is needed on the histological definition for this difficult diagnosis

R. D. Macdonald, J. Kirwan, K. Hayat, C. S. Herrington, H. Shawki

    Research output: Contribution to journalArticlepeer-review

    21 Citations (Scopus)


    Background. Villoglandular adenocarcinoma (VGA) of the cervix is
    reported as a variant of a cervical adenocarcinoma with a good
    prognosis. Cases. We present two cases histologically reported as a
    villoglandular adenocarcinoma of the cervix that have recurred and
    progressed rapidly since initial treatment. External histopathological
    review suggested both had a prominent villoglandular pattern but with an
    associated underlying well-differentiated adenocarcinoma. Conclusion.
    The diagnosis of VGA is difficult. Current literature is not entirely
    consistent in the presented definition, and further clarity is needed.
    Because of the rarity of VGA and the difficulty but importance of the
    diagnosis, we would feel that a central review of all cases of VGA is
    warranted. This would assist in diagnosis and also in obtaining accurate
    follow-up data. © 2005 Elsevier Inc. All rights reserved

    Original languageEnglish
    Pages (from-to)192-194
    Number of pages3
    JournalGynecologic Oncology
    Issue number1
    Publication statusPublished - 2006

    Cite this