Vitamin D and Cardiovascular Prevention

M. Adnan Nadir, Benjamin R. Szwejkowski, Miles D. Witham

    Research output: Contribution to journalReview article

    27 Citations (Scopus)

    Abstract

    Vitamin D has been known to medical science for almost a century. Yet, it is only in the last 15 years that we have realized that the biological effects of vitamin D extend far beyond the control of calcium metabolism. Recent observational evidence suggests strong links between low vitamin D levels and a range of cardiovascular conditions, including stroke, myocardial infarction, hypertension, and diabetes. Interventional studies are beginning to explore whether vitamin D supplementation can modify vascular health and prevent cardiovascular disease. This article reviews the physiology and function of vitamin D, examines the current observational and intervention data in cardiovascular disease, and discusses future research and current practice recommendations.

    Original languageEnglish
    Pages (from-to)e5-e12
    Number of pages8
    JournalCardiovascular Therapeutics
    Volume28
    Issue number4
    DOIs
    Publication statusPublished - 2010

    Keywords

    • Cardiovascular
    • Prevention
    • Treatment
    • Vitamin D
    • NUTRITION EXAMINATION SURVEY
    • 3RD NATIONAL-HEALTH
    • RANDOMIZED CONTROLLED-TRIALS
    • CONGESTIVE-HEART-FAILURE
    • PLACEBO-CONTROLLED TRIAL
    • SOUTH ASIAN WOMEN
    • D SUPPLEMENTATION
    • BLOOD-PRESSURE
    • SERUM 25-HYDROXYVITAMIN-D
    • CALCIUM SUPPLEMENTATION

    Cite this

    Nadir, M. Adnan ; Szwejkowski, Benjamin R. ; Witham, Miles D. / Vitamin D and Cardiovascular Prevention. In: Cardiovascular Therapeutics. 2010 ; Vol. 28, No. 4. pp. e5-e12.
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    author = "Nadir, {M. Adnan} and Szwejkowski, {Benjamin R.} and Witham, {Miles D.}",
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    Vitamin D and Cardiovascular Prevention. / Nadir, M. Adnan; Szwejkowski, Benjamin R.; Witham, Miles D.

    In: Cardiovascular Therapeutics, Vol. 28, No. 4, 2010, p. e5-e12.

    Research output: Contribution to journalReview article

    TY - JOUR

    T1 - Vitamin D and Cardiovascular Prevention

    AU - Nadir, M. Adnan

    AU - Szwejkowski, Benjamin R.

    AU - Witham, Miles D.

    PY - 2010

    Y1 - 2010

    N2 - Vitamin D has been known to medical science for almost a century. Yet, it is only in the last 15 years that we have realized that the biological effects of vitamin D extend far beyond the control of calcium metabolism. Recent observational evidence suggests strong links between low vitamin D levels and a range of cardiovascular conditions, including stroke, myocardial infarction, hypertension, and diabetes. Interventional studies are beginning to explore whether vitamin D supplementation can modify vascular health and prevent cardiovascular disease. This article reviews the physiology and function of vitamin D, examines the current observational and intervention data in cardiovascular disease, and discusses future research and current practice recommendations.

    AB - Vitamin D has been known to medical science for almost a century. Yet, it is only in the last 15 years that we have realized that the biological effects of vitamin D extend far beyond the control of calcium metabolism. Recent observational evidence suggests strong links between low vitamin D levels and a range of cardiovascular conditions, including stroke, myocardial infarction, hypertension, and diabetes. Interventional studies are beginning to explore whether vitamin D supplementation can modify vascular health and prevent cardiovascular disease. This article reviews the physiology and function of vitamin D, examines the current observational and intervention data in cardiovascular disease, and discusses future research and current practice recommendations.

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    KW - Prevention

    KW - Treatment

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    KW - NUTRITION EXAMINATION SURVEY

    KW - 3RD NATIONAL-HEALTH

    KW - RANDOMIZED CONTROLLED-TRIALS

    KW - CONGESTIVE-HEART-FAILURE

    KW - PLACEBO-CONTROLLED TRIAL

    KW - SOUTH ASIAN WOMEN

    KW - D SUPPLEMENTATION

    KW - BLOOD-PRESSURE

    KW - SERUM 25-HYDROXYVITAMIN-D

    KW - CALCIUM SUPPLEMENTATION

    U2 - 10.1111/j.1755-5922.2010.00192.x

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    JF - Cardiovascular Therapeutics

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