What Lies Beneath? Scanning Probe Tomography May Have the Answer

    Research output: Contribution to journalComment/debatepeer-review

    1 Citation (Scopus)

    Abstract

    Scanning probe microscopy facilitates high-resolution noninvasive imaging of surface topography on even the most delicate of biological structures. Moreover, the local probe nature of the instrument architecture lends itself to the measurement of many important physical properties. To date, biological investigations have largely been constrained to imaging surface (membrane)-borne phenomena; however, the advent of extremely high aspect-ratio 'needle' probe tips, as reported by Beard et al. (2013), suggests that the approach can now be extended to address the particular challenges associated with measuring subsurface microscopic targets, including the intracellular components of the stratum corneum.
    Original languageEnglish
    Pages (from-to)1458-1460
    Number of pages3
    JournalJournal of Investigative Dermatology
    Volume133
    Issue number6
    DOIs
    Publication statusPublished - 2013

    Keywords

    • ATOMIC-FORCE MICROSCOPY

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