Yeast protein serine/threonine phosphatases: Multiple roles and diverse regulation

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    Abstract

    Since the isolation of the first yeast protein phosphatase genes in 1989, much progress has been made in understanding this important group of proteins. Yeast contain genes encoding all the major types of protein phosphatase found in higher eukaryotes and the ability to use powerful genetic approaches will complement the wealth of biochemical information available from other systems. This review will summarize recent progress in understanding the structure, function and regulation of the PPP family of protein serine-threonine phosphatases, concentrating on the budding yeast Saccharomyces cerevisiae.

    Original languageEnglish
    Pages (from-to)1647-1675
    Number of pages29
    JournalYeast
    Volume12
    Issue number16
    DOIs
    Publication statusPublished - 1996

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