Abstract
Genome-wide association studies have previously identified variants in SLC30A8, encoding the zinc transporter ZnT8, associated with diabetes risk. A rare variant association study has now established the direction of effect, surprisingly showing that loss-of-function mutations in SLC30A8 are protective against diabetes.
Original language | English |
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Pages (from-to) | 323-4 |
Number of pages | 2 |
Journal | Nature Genetics |
Volume | 46 |
Issue number | 4 |
DOIs | |
Publication status | Published - Apr 2014 |