Content type
Profiles
Search results
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Gilbert, Ian
- Drug Discovery Unit - Professor/Head of the Drug Discovery Unit & Roscoe Chair in Drug Discovery
Person: Academic
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Wyllie, Susan
- Biological Chemistry and Drug Discovery - Professor (Teaching and Research) of Biochemical Pharmacology
Person: Academic
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Research Outputs
Search results
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Drug discovery for the treatment of leishmaniasis, African sleeping sickness and Chagas disease
Avery, V., Buckner, F., Baell, J., Fairlamb, A., Michels, P. A. & Tarleton, R., Oct 2013, In: Future Medicinal Chemistry. 5, 15, p. 1709-1718 10 p.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Neglected tropical diseases and omics science: Proteogenomics analysis of the promastigote stage of leishmania major parasite
Pawar, H., Renuse, S., Khobragade, S. N., Chavan, S., Sathe, G., Kumar, P., Mahale, K. N., Gore, K., Kulkarni, A., Dixit, T., Raju, R., Prasad, T. S. K., Harsha, H. C., Patole, M. S. & Pandey, A., Aug 2014, In: OMICS: A Journal of Integrative Biology (OMICS). 18, 8, p. 499-512 14 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
Current and Future Prospects of Nitro-compounds as Drugs for Trypanosomiasis and Leishmaniasis
Fairlamb, A. H. (Lead / Corresponding author) & Patterson, S., 2019, In: Current Medicinal Chemistry. 26, 23, p. 4454-4475 22 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile45 Citations (Scopus)663 Downloads (Pure) -
Chemotherapy of human African trypanosomiasis: current and future prospects
Fairlamb, A. H., 1 Nov 2003, In: Trends in Parasitology. 19, 11, p. 488-494 7 p.Research output: Contribution to journal › Review article › peer-review
295 Citations (Scopus) -
Finding New Hits in Neglected Disease Projects: Target or Phenotypic Based Screening?
Gilbert, I. H., Leroy, D. & Frearson, J. A., May 2011, In: Current Topics in Medicinal Chemistry. 11, 10, p. 1284-1291 8 p.Research output: Contribution to journal › Review article › peer-review
31 Citations (Scopus) -
Fexinidazole for the treatment of human African trypanosomiasis
Fairlamb, A. (Lead / Corresponding author), Dec 2019, In: Drugs of Today . 55, 11, p. 705-712 8 p., 705.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus)
Projects
Search results
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A Pipeline of Drugs for Visceral Leishmaniasis and Chagas Disease Through Expertise and Innovation (Preliminary Strategic Award) (Joint with Glaxosmithkline)
Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Horn, D. (Investigator), Read, K. (Investigator) & Wyatt, P. (Investigator)
Project: Research
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Converting Natural Product Leads into Structure and Ligand Based Drug Discovery Campaigns against Leishmaniasis and Chagas' Disease (Joint with Sao Paulo State University)
Gilbert, I. (Investigator), Read, K. (Investigator) & Wyllie, S. (Investigator)
1/04/19 → 31/03/22
Project: Research
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Fighting Malaria: PfGNA1 as a Novel Malaria Drug Target
Baragana, B. (Investigator), Gilbert, I. (Investigator) & Postis, V. (Investigator)
Project: Research
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Pilot Study of Aminacyl-Acid tRNA Synthetases as Drug Targets for TB and Malaria
Gilbert, I. (Investigator)
Bill and Melinda Gates Foundation
1/12/20 → 31/12/25
Project: Research
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Aref#d: 18913. Development of a diagnostic tool for leishmaniasis (Capacity Building Studentship)
Ferguson, M. (Investigator) & Nikolaev, A. (Investigator)
Project: Research
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Optimisation of Multistage Inhibitors of P. Falciparum Lysyl-t-RNA Synthetase for the Treatment of Malaria (joint with Eisai Pharmaceuticals and Medicines for Malaria Venture)
Gilbert, I. (Investigator), Gray, D. (Investigator), Read, K. (Investigator) & Wyatt, P. (Investigator)
1/04/21 → 31/03/23
Project: Research
Datasets
Search results
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Modelling data for: Short-course combination treatment for experimental chronic Chagas disease
González Del Valle, S. (Creator), Zuccotto, F. (Creator), Luise, C. (Creator), Wyllie, S. (Creator) & De Rycker, M. (Creator), Dryad, 14 Dec 2023
DOI: 10.5061/dryad.95x69p8r7, https://datadryad.org/stash/dataset/doi:10.5061/dryad.95x69p8r7
Dataset
Theses
Search results
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Discovery and development of diagnostic biomarkers for human African trypanosomiasis
Sullivan, L. (Author), Ferguson, M. (Supervisor), 2012Student thesis: Doctoral Thesis › Doctor of Philosophy
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Arsenic, antimony and visceral leishmaniasis
Perry, M. R. (Author), Fairlamb, A. (Supervisor), 2014Student thesis: Doctoral Thesis › Doctor of Philosophy
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Structure- based inhibitor design for key enzymes of Tryposoma brucei
Striker, W. (Author), Brenk, R. (Supervisor), 2014Student thesis: Doctoral Thesis › Doctor of Philosophy
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Proteomic analysis of protein complexes and cell cycle regulation in Trypanosoma brucei
Crozier, T. W. M. (Author), Ferguson, M. (Supervisor) & Lamond, A. (Supervisor), 2016Student thesis: Doctoral Thesis › Doctor of Philosophy
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Chemical synthesis of Leishmania lipophosphoglycan structures conjugated to a biotin moiety
Edgar, C. W. (Author), Nikolaev, A. (Supervisor), 2011Student thesis: Doctoral Thesis › Doctor of Philosophy
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Synthetic strategies for potential trypanocides
Capes, A. (Author), Gilbert, I. (Supervisor), 2011Student thesis: Doctoral Thesis › Doctor of Philosophy
Activity
Search results
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Neglected Tropical Diseases Festival 2018
Duce, S. (Speaker)
27 Mar 2018Activity: Participating in or organising an event types › Festival/Exhibition
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PLoS Neglected Tropical Diseases (Journal)
De Rycker, M. (Peer reviewer)
14 Aug 2023Activity: Publication peer-review and editorial work types › Publication peer-review
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PLoS Neglected Tropical Diseases (Journal)
De Rycker, M. (Peer reviewer)
29 Apr 2024Activity: Publication peer-review and editorial work types › Publication peer-review
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Neglected Tropical Diseases Festival 2019
Duce, S. (Contributor)
11 Mar 2019Activity: Participating in or organising an event types › Festival/Exhibition
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Drug discovery for Neglected Tropical Diseases
De Rycker, M. (Speaker)
8 Apr 2022Activity: Talk or presentation types › Invited talk
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Drug Discovery for Neglected Tropical Diseases; applying lessons from trypanosomatid drug discovery to Cryptococcus
De Rycker, M. (Speaker)
15 Jul 2023Activity: Talk or presentation types › Invited talk
Press/Media
Search results
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Potential new treatment identified for Leishmaniasis
1/02/12 → 2/02/12
2 items of Media coverage
Press/Media: Research
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Tuberculosis drug may also target visceral leishmaniasis
24/05/16
1 item of Media coverage
Press/Media: Research
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Sleeping sickness parasite's pores act as efficient drug uptake mechanism
26/11/13
3 items of Media coverage
Press/Media: Research
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Drug breakthrough in fight against neglected diseases
Wyatt, P., Fairlamb, A. H. & Ferguson, M. A. J.
1/04/10
1 item of Media coverage
Press/Media: Research
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Researchers uncover new operations of cancer suppressor
Nicholas R. Leslie
24/02/12
4 items of Media coverage
Press/Media: Research
Research Facilities
Search results
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Fingerprints Proteomics Facility
Centre for Advanced Scientific TechnologiesFacility/equipment: Facility
Prizes
Search results
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Neglected Tropical Diseases Festival Writing Award
Duce, S. (Recipient), Mar 2019
Prize: Prize (including medals and awards)
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Neglected Tropical Diseases Festival Art Award
Duce, S. (Recipient), Mar 2018
Prize: Prize (including medals and awards)
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3Rs Prize 2006 for Refinement and Reduction of Animal Models of Leishmaniasis
Fairlamb, A. (Recipient) & Wyllie, S. (Recipient), 2006
Prize: Prize (including medals and awards)
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Member of the Board of Directors of the Medicines for Malaria Venture (MMV)
Ferguson, M. (Recipient), 1 Jan 2012
Prize: Appointment
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