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Dual regulation of transcription factor Nrf2 by Keap1 and the beta-TrCP/GSK-3 in cancer

Author: Ebisine, K., 2019

Supervisor: Hayes, J. (Supervisor) & Dinkova-Kostova, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Metabolic Factors Determining Outcome in Chemotherapy: Studies with Pazopanib

Author: Sharp, S. L., 2014

Supervisor: Wolf, C. (Supervisor) & Henderson, C. J. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Catalytic and non-catalytic mechanisms involved in Glutathione S-transferase Pi mediated cytoprotection

Author: McGarry, D., 2012

Supervisor: Henderson, C. J. (Supervisor) & Wolf, C. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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A Comprehensive Analysis of SGLT2-inhibition in Type 2 Diabetes and Heart Failure

Author: Singh, J., 2019

Supervisor: Lang, C. (Supervisor) & Struthers, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Medicine

The Acute Effects of Allopurinol in Angina

Author: Shearer, F., 2018

Supervisor: Struthers, A. (Supervisor) & Lang, C. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Medicine

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Thermally-induced ratcheting behaviour of laterally-loaded reinforced concrete energy piles in sand

Author: Zhao, R., 2020

Supervisor: Knappett, J. (Supervisor), Leung, A. (Supervisor) & Anastasopoulos, I. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Corporate Governance as a Transformation Tool in Sustaining Nigeria’s Small and Medium-Sized Enterprises (SMEs)

Author: Ugowe, A. O. O., 2020

Supervisor: Belcher, A. (Supervisor), El Droubi, S. (Supervisor) & Shields, K. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Use of Human Reliability Analysis to evaluate surgical technique for rectal cancer

Author: Wilson, P. J., 2012

Supervisor: Steele, R. (Supervisor) & Hanna, G. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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A Quantitative Exploration of Causes of False Positive Single Nucleotide Polymorphisms in Next-Generation Sequencing Data

Author: Bello Ribeiro, A. C., 2016

Supervisor: Flavell, A. (Supervisor), Bayer, M. (Supervisor) & Marshall, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Exploiting crosstalk between growth and immunity in plants : the role of the Phytophthora infestans effector AVR2 in potato late blight

Author: Turnbull, D., 2016

Supervisor: Birch, P. (Supervisor), Gilroy, E. (Supervisor) & Hein, I. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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The Regulation of Oncogenic MAP Kinase Signalling by Dual-Specificity MAP Kinase Phosphatases

Author: Kidger, A. M., 2016

Supervisor: Keyse, S. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Regulation of β2-integrins by signalling pathways and cytoplasmic interacting partners

Author: Lek, H. S., 2015

Supervisor: Fagerholm, S. (Supervisor) & Sutherland, C. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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In vitro reconstitution of the ubiquitylation and disassembly of the eukaryotic replisome

Author: Mukherjee, P., 2018

Supervisor: Labib, K. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Neurosteroids: endogenous analgesics?

Author: Humble, S. R., 2013

Supervisor: Lambert, J. (Supervisor), Hales, T. (Supervisor) & Belelli, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Science

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The role of central IL-6 signalling in the development of Type 2 Diabetes

Author: Yiannakas, A., 2016

Supervisor: McCrimmon, R. (Supervisor) & Ashford, M. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Characterisation of leptin mimetic agents as therapeutic targets in Alzheimer's disease

Author: Malekizadeh, Y., 2016

Supervisor: Harvey, J. (Supervisor) & Irving, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

The role of Integrin-Linked Kinase in regulating glucose and lipid homeostasis in adipose tissue

Author: Bugler-Lamb, A., 2020

Supervisor: Kang, L. (Supervisor) & Ashford, M. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Age-dependent regulation of hippocampal excitatory synaptic transmission by leptin

Author: Mcgregor, G., 2018

Supervisor: Harvey, J. (Supervisor) & Irving, A. J. (External person) (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

The characterisation of ion channels in human spermatozoa by whole cell patch clamp electrophysiology

Author: Mansell, S. A., 2013

Supervisor: Barratt, C. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Investigating the effect of phosphodiesterase inhibitors on human sperm motility and function

Author: Rice, A., 2011

Supervisor: Barratt, C. (Supervisor)

Student thesis: Master's ThesisMaster of Science

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The cavitation subharmonic signal : mechanistic source and optimised detection

Author: Johnston, K., 2016

Supervisor: Prentice, P. (Supervisor), Cochran, S. (Supervisor) & Cuschieri, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Quantitative Deubiquitinase (DUB) Interactomics to Dissect the Biology of Cancer Associated DUBs

Author: Natarajan, J., 2019

Supervisor: Kulathu, Y. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Role of Chromatin Structure and JmjC Histone Demethylases in the Response to Hypoxia

Author: Batie, M., 2017

Supervisor: Rocha, S. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Investigating the clinical value of hyperactivation and intracellular calcium signalling of human spermatozoa and their value in drug screening

Author: Ruso, H., 2013

Supervisor: Martins Da Silva, S. (Supervisor) & Barratt, C. (Supervisor)

Student thesis: Master's ThesisMaster of Science

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Compounds Modulating Calcium and Motility in Human Spermatozoa

Author: Cochrane, C., 2015

Supervisor: Barratt, C. (Supervisor) & Martins Da Silva, S. (Supervisor)

Student thesis: Master's ThesisMaster of Science

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Novel Modulators of Human Sperm Motility

Author: King, L., 2014

Supervisor: Martins Da Silva, S. (Supervisor) & Barratt, C. (Supervisor)

Student thesis: Master's ThesisMaster of Science

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Elastic Characterization of ex vivo Human Prostate Tissue Using Vibration Optical Coherence Elastography and Second Harmonic Generation Microscopy

Author: Ling, Y., 2018

Supervisor: Huang, Z. (Supervisor), McGloin, D. (Supervisor) & Nabi, G. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Safety Evaluation of Surgical Instruments

Author: Xu, Y., 2017

Supervisor: Huang, Z. (Supervisor) & Corner, G. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Magnetic Resonance Assessment of Aortic Stiffness in Diabetes and Cardiovascular Disease

Author: Cassidy, D., 2014

Supervisor: Houston, J. (Supervisor), Gandy, S. (Supervisor) & Khan, F. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Development of MRI-compatible Transducer Array for Focused Ultrasound Surgery: : The Use of Relaxor-based Piezocrystals

Author: Qiu, Z., 2014

Supervisor: Cochran, S. (Supervisor) & Huang, Z. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Analysis of the diverse antibacterial strategies used by Serratia marcescens Db10

Author: Gerc, A., 2014

Supervisor: Stanley-Wall, N. (Supervisor) & Coulthurst, S. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Standardisation and quality assurance of 2D ultrasound Shear Wave Elastography imaging in breast tissue

Author: Skerl, K., 2016

Supervisor: Evans, A. (Supervisor) & Cochran, S. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Genomic investigation into the evolution of Staphylococcus aureus and the micro-epidemiology of Staphylococcus aureus in atopic eczema

Author: Harkins, C. P., 2016

Supervisor: Proby, C. (Supervisor) & Holden, M. T. G. (External person) (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Epigenetic dysregulation of novel candidate genes in melanoma

Author: Wang, H., 2013

Supervisor: Proby, C. (Supervisor), Crook, T. (Supervisor) & Inman, G. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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An analysis of the utility of quantitative faecal immunochemical tests in screening and symptomatic populations

Author: Mcdonald, P. J., 2016

Supervisor: Steele, R. (Supervisor) & Bartlett, W. (External person) (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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The impact of a single brief intervention versus multiple contact lifestyle intervention on change in body weight and modifiable cardio vascular risk factors in adults who have undertaken cardiovascular risk screening

Author: Rowland, J., 2016

Supervisor: Belch, J. (Supervisor), Anderson, A. (Supervisor), Craigie, A. (Supervisor), Littleford, R. (Supervisor) & Bannerman, E. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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The relationship between faecal haemoglobin concentration and risk of significant colorectal neoplasia in screening and symptomatic populations.

Author: Digby, J., 2016

Supervisor: Steele, R. (Supervisor) & Fraser, C. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Molecular characterisation of the Rhynchosporium commune interaction with barley

Author: Gamble, M., 2016

Supervisor: Birch, P. (Supervisor), Avrova, A. O. (External person) (Supervisor) & Newton, A. C. (External person) (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Approaches to understanding diversity in rubber and carotenoid synthesis in Hevea brasiliensis latex

Author: Bahari, A., 2019

Supervisor: Marshall, D. (Supervisor), Taylor, M. (Supervisor), Chow, K. (External person) (Supervisor), Campbell, R. (External person) (Supervisor) & Halpin, C. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Regulation of dorsal raphe serotonergic neurons by histamine

Author: Panetta, K. M., 2014

Supervisor: Belelli, D. (Supervisor), Lambert, J. (Supervisor) & Wafford, K. A. (External person) (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Opioid modulation of AMPA receptors: A new target to treat mood disorders and cognitive dysfunction

Author: Mariano, A., 2019

Supervisor: Langston, R. (Supervisor) & Lambert, J. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Cognitive and synaptic dysfunction in a mouse model of Huntington's disease

Author: Mitchell, R. C., 2012

Supervisor: Schweiger, S. (Supervisor), Langston, R. (Supervisor), Lambert, J. (Supervisor) & Belelli, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Population dynamics of potato cyst nematodes in relation to temperature

Author: Kaczmarek, A., 2014

Supervisor: Birch, P. (Supervisor) & Blok, V. C. (External person) (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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The effects of intra-dorsal raphe administration of strychnine on rat behaviour and its interactions with ethanol

Author: Greig, S. J., 2013

Supervisor: Lambert, J. (Supervisor), Balfour, D. (Supervisor) & Belelli, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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An investigation of gene expression, alternative splicing and nonsense-mediated decay in potato in response to Phytophthora infestans infection

Author: Domingo Torres, E., 2019

Supervisor: Brown, J. (Supervisor), Simpson, C. (Supervisor) & Hein, I. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Regulation of low-temperature alternative splicing in the Arabidopsis thaliana circadian clock genes

Author: Tzioutziou, N., 2016

Supervisor: Brown, J. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Nonlinear Nonlocal Parabolic-Hyperbolic Coupled Systems for Cancer Cell Movement and Aggregation

Author: Bitsouni, V., 2017

Supervisor: Eftimie, R. (Supervisor) & Chaplain, M. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Neuropsychological function as a result of chronic exposure to methadone and other opioids

Author: Baldacchino, A., 2012

Supervisor: Matthews, K. (Supervisor) & Balfour, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Genetic and non-genetic determinants of drug response in type 2 diabetes

Author: Dawed, A. Y., 2017

Supervisor: Pearson, E. (Supervisor) & Zhou, K. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Medicine