Characterising the recruitment and activation mechanisms of the mRNA capping enzymes via molecular dynamics simulation

Marcus G. Bage

Student thesis: Doctoral Thesis › Doctor of Philosophy

Date of Award	2021
Original language	English
Awarding Institution	University of Dundee
Sponsors	Medical Research Council
Supervisor	Andrei Pisliakov (Supervisor) & Victoria Cowling (Supervisor)

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Links

Publication relating to the work described in chapter 3 of the thesis.

Publication relating to the work described in chapter 4 of the thesis.

Related content

Research Outputs
Mechanism of allosteric activation of human mRNA cap methyltransferase (RNMT) by RAM: Insights from accelerated molecular dynamics simulations
Research output: Contribution to journal › Article › peer-review
A novel RNA Pol II CTD interaction site on the mRNA Capping Enzyme is essential for its allosteric activation
Research output: Contribution to journal › Article › peer-review

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