Prevalence of left ventricular hypertrophy in peripheral arterial disease and its relation to blood pressure

  • Gary Allan Wright

    Student thesis: Doctoral ThesisDoctor of Medicine


    Objectives: To assess the prevalence of left ventricular hypertrophy (LVH) inpatients with newly diagnosed peripheral arterial disease (PAD).

    Methods: Consecutive patients referred for the first time for assessment of PAD with a history of intermittent claudication and ankle brachial pressure of index of ≤0.9 were recruited. All subjects underwent a full echocardiogram, office blood pressure and 24 hour ambulatory blood pressure monitoring.

    Results: Out of 350 subjects screened, left ventricular mass measurements were available on 227 (65%). The prevalence of LVH indexed to body surface area was 50%. In a multiple regression model the factors independently related to LVH were age, sex and history of diabetes. There was no relation between presence of LVH and 24 hour blood pressure.

    Conclusion: LVH is prevalent in patients with PAD and is not associated with 24 hour blood pressure.
    Date of Award2014
    Original languageEnglish
    SponsorsChief Scientist Office
    SupervisorAllan Struthers (Supervisor)

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